Clinical and Experimental Reproductive Medicine

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Original Article

July 20, 2021

Protective effects of curcumin against methotrexate-induced testicular damage in rats by suppression of the p38-MAPK and nuclear factor-kappa B pathways

Leyla Kilinc, Yesim Hulya Uz

Clin Exp Reprod Med. 2021;48(3):211-220.

Objective: Methotrexate (MTX), is a commonly used chemotherapeutic agent. This study aimed to investigate the possibility that curcumin (CMN) protects against MTX-induced testicular damage by affecting the phospho (p)-p38 mitogen-activated...

Original Article

August 26, 2021

Effects of crocin and metformin on methylglyoxal-induced reproductive system dysfunction in diabetic male mice

Maryam Kheirollahi Khorasani, Akram Ahangarpour, Layasadat Khorsandi

Clin Exp Reprod Med. 2021;48(3):221-228.

Objective: This study investigated the effect of crocin in methylglyoxal (MGO)-induced diabetic male mice. Methods: Seventy 1-month-old male NMRI mice weighing 20–25 g were divided into seven groups (n=10): sham, MGO...

Original Article

August 26, 2021

Effects of cholesterol and Lactobacillus acidophilus on testicular function

Gülay Çiftci, Elif Tuna

Clin Exp Reprod Med. 2021;48(3):229-235.

Objective: In this study, the effects of Lactobacillus acidophilus on testosterone (TES), follicle-stimulating hormone (FSH), luteinizing hormone (LH), androgen-binding protein (ABP), factor-associated apoptosis (FAS), and total cholesterol (TC), as well...

Original Article

August 20, 2021

The effect of genistein on insulin resistance, inflammatory factors, lipid profile, and histopathologic indices in rats with polycystic ovary syndrome

Sasan Amanat, Fatemeh Ashkar, Mohammad Hassan Eftekhari, et al.

Clin Exp Reprod Med. 2021;48(3):236-244.

Objective: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, irregular menstruation, ovulatory dysfunction, and insulin resistance. Recent studies have reported the possible role of phytoestrogens in PCOS. This animal study...

Original Article

August 6, 2021

Alteration of TGFB1, GDF9, and BMPR2 gene expression in preantral follicles of an estradiol valerate-induced polycystic ovary mouse model can lead to anovulation, polycystic morphology, obesity, and absence of hyperandrogenism

Reza Asghari, Vahid Shokri-Asl, Hanieh Rezaei, et al.

Clin Exp Reprod Med. 2021;48(3):245-254.

Objective: In humans, polycystic ovary syndrome (PCOS) is an androgen-dependent ovarian disorder. Aberrant gene expression in folliculogenesis can arrest the transition of preantral to antral follicles, leading to PCOS. We...

Original Article

September 1, 2021

Predictive value of sperm motility before and after preparation for the pregnancy outcomes of intrauterine insemination

Mina Jeong, Seul Ki Kim, Hoon Kim, et al.

Clin Exp Reprod Med. 2021;48(3):255-261.

Objective: This study aimed to investigate sperm motility and its changes after preparation as predictors of pregnancy in intrauterine insemination (IUI) cycles. Methods: In total, 297 IUI cycles from January 2012...

Original Article

August 9, 2021

Subcutaneous progesterone versus vaginal progesterone for luteal phase support in in vitro fertilization: A retrospective analysis from daily clinical practice

Marcel Schütt, The Duy Nguyen, Martha Kalff-Suske, et al.

Clin Exp Reprod Med. 2021;48(3):262-267.

Objective: Progesterone application for luteal phase support is a well-established concept in in vitro fertilization (IVF) treatment. Water-soluble subcutaneous progesterone injections have shown pregnancy rates equivalent to those observed in...

Current Issue: Volume 48(3); Sep 2021

Administration of red ginseng regulates microRNA expression in a mouse model of endometriosis

Jae Hoon Lee, Ji Hyun Park, Bo Hee Won, et al.

[Epub ahead of print]

Original Article

September 1, 2021

Delayed postpartum regression of theca lutein cysts with maternal virilization: A case report

Sanghwa Kim, Inha Lee, Eunhyang Park, et al.

[Epub ahead of print]

Case Report

August 30, 2021

Editorial Office: Department of Obstetrics and Gynecology CHA Bundang Medical Center, CHA University
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Copyright © 2021 by Korean Society for Reproductive Medicine.

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