Korean J Fertil Steril Search

CLOSE


Korean Journal of Fertility and Sterility 2002;29(4):311-316.
Published online December 1, 2002.
Association Study of the Relationship between Endometriosis and Polymorphism of p53 Codon 72.
Sung Eun Hur, Soung Shin Shim, Kyung Soon Lee, Hye Sung Moon, Han Ki Yu, Hye Won Chung
Department of Obstetrics and Gynecology, College of Medicine, Ewha Womans' University. Korea.
Abstract
OBJECTIVE
The present study was performed to evaluate the association of p53 codon 72 polymorphism and endometriosis. MATERIALS AND METHODS: We investigate 74 women who were operated for endometriosis and 93 women who had no endometriotic lesion proved by operation. Polymerase chain reaction was used to detect p53 codon polymorphisms. Result: We have found no significant difference between endometriosis and control group in the p53 codon polymorphism. The respective proportion of arginine homozygotes, heterozygotes and proline homozygotes in endometriosis group were 18.9%, 62.2% and 18.9%, respectively, and were 12.9%, 75.2% and 11.9%, respective in the group without endometriosis. CONCLUSION: Endometriosis is not associated with p53 polymorphism in Korean endometriosis patients.
Key Words: Endometriosis; p53; Polymorphism; Arginine; Proline


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
Department of Obstetrics and Gynecology CHA Bundang Medical Center, CHA University
59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, Korea
Tel: +82-31-727-8701    CP: +82-10-9072-3154    E-mail: hwas0605@cha.ac.kr                

Copyright © 2023 by Korean Society for Reproductive Medicine.

Developed in M2PI

Close layer
prev next