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Korean Journal of Fertility and Sterility 2001;28(4):301-306.
Published online December 1, 2001.
The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion.
Yoon Sung Nam, Kwang Yul Cha, Nam Keun Kim, Myung Seo Kang, Doyeon Oh
1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
2Institute for Clinical Research, College of Medicine, Pocheon CHA University, Pocheon, Korea.
OBJETIVE: To analyze the antithrombin III deficiency in patients with recurrent spontaneous abortion. MATERIALS AND METHOD: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III. RESULTS: There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT. CONCLUSIONS: Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients.
Key Words: Recurrent spontaneous abortion; Antithrombin III deficiency


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