A Case of Recurrent Spontaneous Abortion Successfully Delivered by Using Preimplantation Genetic Diagnosis.

Nam,  Yoon Sung; Lee,  Sook Hwan; Oum,  Ki Bung; Lee,  Eun Jung; Chung,  Hyung Min; Cha,  Kwang Yul

In Vitro

Korean Journal of Fertility and Sterility 2000;27(3):307-311.
Published online January 1, 2001.

A Case of Recurrent Spontaneous Abortion Successfully Delivered by Using Preimplantation Genetic Diagnosis.

Yoon Sung Nam, Sook Hwan Lee, Ki Bung Oum, Eun Jung Lee, Hyung Min Chung, Kwang Yul Cha

Abstract

OBJECTIVE
To report the successful delivery in a patient of recurrent spontaneous abortion caused by chromosomal abnormality. MATERIAL AND METHOD: Case report. RESULTS: Twelve oocytes were obtained by in vitro fertilization. Of eleven oocytes fertilized, two embryos turned out to be normal by using fluorescent in situ hybridization on blastomere biopsy. The patient succeeded in pregnancy and the result of amniocentesis was found to be normal. She delivered the healthy female baby by cesarean section. CONCLUSIONS: The successful delivery is possible in recurrent spontaneous abortion related with reciprocal translocation by using preimplantation genetic diagnosis.