Korean J Fertil Steril Search

CLOSE


Korean Journal of Fertility and Sterility 2006;33(2):133-138.
Published online June 1, 2006.
A Case of Male Pseudohermaphroditism due to 17alpha-Hydroxylase Deficiency.
Keoung Ah Park, Youn Kyung Chung, Jung Ryeol Lee, Young Min Choi, Gyoung Hoon Lee, Hee Seung Kim, Byung Chul Jee, Seung Yup Ku, Chang Suk Suh, Seok Hyun Kim, Jung Gu Kim, Shin Yong Moon, Seong Yeon Kim
1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
2Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.
3Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Abstract
Female phenotype of a 46,XY male may originates from male pseudohermaphroditism due to 17alpha-hydroxylase deficiency. Lack of cortisol increases adrenocorticotropic hormone (ACTH) and mineralocorticoid production, leading to low renin hypertention and hypokalemia. A 41-year-old phenotypic female presented primary amenorrhea and hypertension. In the hormonal profile, the levels of serum estradiol, testosterone, rennin, and cortisol were decreased and ACTH and deoxycorticosterone were increased. Laparoscopic bilateral gonadectomy was performed, and corticosteroid, antihypertensive drugs, and estrogen were administered. We report this case with a brief review of the literatures.
Key Words: 17alpha-hydroxylase deficiency; Male pseudohermaphroditism; Congenital adrenal hyperplasia
TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 66 View
  • 0 Download
Related articles in Clin Exp Reprod Med

A case of 17 alpha-hydroxylase deficiency2015 June;42(2)



ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital,
82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13620, Korea
Tel: +82-31-787-7254    Fax: +82-31-787-4054    E-mail: blasto@snubh.org                

Copyright © 2019 by Korean Society for Reproductive Medicine. All rights reserved.

Developed in M2community

Close layer
prev next