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Korean Journal of Fertility and Sterility 1986;13(2):161-174.
A Study of Chromosomal Abnormality in Urological Patients
Kwang-Myung Kim1, Hwang Choi1, Sun-Kyung Oh2, Shin-Yong Moon2
1Department of Urology, College of Medicine, Seoul National University
2Department of Obstetrics and Gynecology, College of Medicine, Seoul National University
비뇨기과 환자에서의 염색체 이상에 관한 연구
김광명1, 최황1, 오선경2, 문신용2
1서울대학교 의과대학 비뇨기과학교실
2서울대학교 의과대학 산부인과학교실
Abstract
A chromosomal study was performed in a total of 162 urological patients during past 2$2{\frac{1}{2}}$ years (Feb. 1984 - Aug. 1986). Of these 78(48%) patients had abnormal chromosome complements. Among all patients with chromosome abnormalities, 88% (69/78) had aberrations of chromosome number, 8% (6/78) had aberrations of chromosome structure and 4% (3/78) had aberrations of both. 90% (65/72) of numerical abnormality was Klinefelter's syndrome and the structural abnormality rate (5.6%, 9/162) was less than that (6.99%) of general population. The chromosomal study was mandatory for the detection of intersex in small testes or hypospadias with cryptorchism or clitoromegaly or bilateral cryptorchism. But unilateral cryptochism or hypospadias with normal scrotal testes was not thought to be indication of the chromosomal study if the external genitalia are otherwise quite normal.


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