A Case of Antiphospholipid Syndrome Associated with Protein C Deficiency.

Nam,  Y S; Han,  S Y; Choi,  D H; Yoon,  T K; Cha,  K Y

Case Report

Korean Journal of Fertility and Sterility 1999;26(1):123-126.
Published online January 1, 2001.

A Case of Antiphospholipid Syndrome Associated with Protein C Deficiency.

Y S Nam, S Y Han, D H Choi, T K Yoon, K Y Cha

Abstract

A successful outcome of pregnancy requires an efficient uteroplacental vascular system. Since this system may be compromised by disorders of haemostasis associated with a prothrombotic state, maternal thrombophilia might be a risk factor for fetal loss. Hereditary deficiencies of the naturally occuring anticoagulants are well recognized conditions predisposing to recurrent venous thromboembolism. Since thrombotic phenomena have been implied as a cause of abortion and stillbirth, these deficiencies might increase the risk of fetal demise. We have experienced a case of antiphospholipid syndrome associated with protein C deficiency in patient with recurrent spontaneous abortion. So we report this case with a brief review of literatures.