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Korean Journal of Fertility and Sterility 1990;17(1):57-63.
Study on Pregnancy and Improvement of Fertilization rate by Micromanipulation (Partial Zona Dissection (PZD) and Micro-Insemination by Sperm Transfer(MIST) in human IVF-ET
Ho-Joon Lee1, Kyoo-Wan Choi1, Jong-Yung Jun1, Jong-Min Park1, Hyuck-Chan Kwon1, Moon-Kyoo Kim2
1IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital
2Department of Biology, College of Natural Science, Hanyang University
체외수정시술시 미세조작술에 의한 수정률 향상과 임신에 관한 연구
이호준1, 최규완1, 전종영1, 박종민1, 권혁찬1, 김문규2
1제일병원 산부인과 체외수정 연구실
2한양대학교 자연과학대학 생물학과
Abstract
The purpose of this study is to improve fertilization rate in IVF-ET program of patients with male infertility used micromanipulation technique, partial zona dissection (PZD) or micro-insemination by sperm transfer (MIST). The results were as follows 1. The fertilization rate of non-micromanipulated oocytes and micromanipulated (PZD) oocytes were 12.5% (n=2) and 42.2% (n=19), respectively, and showed significant differences between two groups (p<0.05). 2. The fertilization rate of micromanipulated (MIST) oocytes was 30% (n=27). 3. The damage rate of Group 1 (PZD) and Group 2 (MIST) were 15.7% (3/19) and 29.6% (8/27), respectively. 4. One pregnancy resulted following replacement of micromanipulated (MIST) embryos in 4 patients.
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