A Cytogenetic Study of 82 Korean Patient with Turner's Syndrome

Moon,  Shin-Yong; Jung,  Young-Hoon; Cha,  Sang-Heon; Park,  Tae-Dong; Lee,  Jin-Yong; Chang,  Yoon-Seok; Song,  Jeong-Ja; Choe,  Gyu-Wan

Original Article

Korean Journal of Fertility and Sterility 1985;12(1):99-108.

Shin-Yong Moon¹, Young-Hoon Jung¹, Sang-Heon Cha¹, Tae-Dong Park¹, Jin-Yong Lee¹, Yoon-Seok Chang¹, Jeong-Ja Song², Gyu-Wan Choe³

¹Department of Obstetrics & Gynecology, College of Medicine, Seoul National University
²Internal Medicine and Institute of Reproductive Medicine and Population, Seoul National University
³Internal College of Medicine, Seoul National University

한국인(韓國人) Turner 증후군(症候群)의 세포유전학적(細胞遺傳學的) 연구(硏究)

문신용¹, 정영훈¹, 차상헌¹, 박태동¹, 이진용¹, 장윤석¹, 송정자², 최규완³

¹서울대학교의과대학 산부인과학교실
²서울대학교 인구의학연구소 세포유전학 연구소
³서울대학교 의과대학 내과학교실

Abstract

The purpose of this study is to investigate .the cytogenetic characteristics of the Turner's syndrome in Korea. For this study selected were eighty-two patients with Turner's syndrome, who were diagnosed by the chromosomal analyses of the cultured peripheral blood lymphocytes, at the Cytogenetic Laboratory, Institute of Reproductive Medicine and Population, College of Medicine, Seoul National University, for the period of 11 years and 6 months from May 1971 through November 1982. Among the 82 patients with Turner's syndrome, 21 (25.6%) had 45,X karyotype, 57 (69.4%) had mosaicism of 45,X/46,XX (39), 45, X/46, XX/47, XXX (9), 45, X/47, XXX (5), 45, X/46, XY (4). Remaining 4 patients had 46, $XX_{p-}$, 46, $XX_{q-}$and 46,X,i($X_q$), respectively.