| The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion. |
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Yoon Sung Nam, Kwang Yul Cha, Nam Keun Kim, Myung Seo Kang, Doyeon Oh |
1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
2Institute for Clinical Research, College of Medicine, Pocheon CHA University, Pocheon, Korea. |
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| Abstract |
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OBJETIVE: To analyze the antithrombin III deficiency in patients with recurrent spontaneous abortion. MATERIALS AND METHOD: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III. RESULTS: There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT. CONCLUSIONS: Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients. |
| Key Words:
Recurrent spontaneous abortion; Antithrombin III deficiency |
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