| Study on Pregnancy and Improvement of Fertilization rate by Micromanipulation (Partial Zona Dissection (PZD) and Micro-Insemination by Sperm Transfer(MIST) in human IVF-ET |
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Ho-Joon Lee1, Kyoo-Wan Choi1, Jong-Yung Jun1, Jong-Min Park1, Hyuck-Chan Kwon1, Moon-Kyoo Kim2 |
1IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital
2Department of Biology, College of Natural Science, Hanyang University |
| 체외수정시술시 미세조작술에 의한 수정률 향상과 임신에 관한 연구 |
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이호준1, 최규완1, 전종영1, 박종민1, 권혁찬1, 김문규2 |
1제일병원 산부인과 체외수정 연구실
2한양대학교 자연과학대학 생물학과 |
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| Abstract |
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The purpose of this study is to improve fertilization rate in IVF-ET program of patients with male infertility used micromanipulation technique, partial zona dissection (PZD) or micro-insemination by sperm transfer (MIST). The results were as follows 1. The fertilization rate of non-micromanipulated oocytes and micromanipulated (PZD) oocytes were 12.5% (n=2) and 42.2% (n=19), respectively, and showed significant differences between two groups (p<0.05). 2. The fertilization rate of micromanipulated (MIST) oocytes was 30% (n=27). 3. The damage rate of Group 1 (PZD) and Group 2 (MIST) were 15.7% (3/19) and 29.6% (8/27), respectively. 4. One pregnancy resulted following replacement of micromanipulated (MIST) embryos in 4 patients. |
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